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Dual conformational recognition by Z-DNA binding protein is important for the B–Z transition process

Left-handed Z-DNA is radically different from the most common right-handed B-DNA and can be stabilized by interactions with the Zα domain, which is found in a group of proteins, such as human ADAR1 and viral E3L proteins. It is well-known that most Zα domains bind to Z-DNA in a conformation-specific...

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Detalles Bibliográficos
Autores principales: Park, Chaehee, Zheng, Xu, Park, Chan Yang, Kim, Jeesoo, Lee, Seul Ki, Won, Hyuk, Choi, Jinhyuk, Kim, Yang-Gyun, Choi, Hee-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736808/
https://www.ncbi.nlm.nih.gov/pubmed/33245772
http://dx.doi.org/10.1093/nar/gkaa1115