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Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their ana...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/ https://www.ncbi.nlm.nih.gov/pubmed/33335413 http://dx.doi.org/10.2147/CCID.S286411 |
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author | Baswan, Sudhir M Klosner, Allison E Glynn, Kelly Rajgopal, Arun Malik, Kausar Yim, Sunghan Stern, Nathan |
author_facet | Baswan, Sudhir M Klosner, Allison E Glynn, Kelly Rajgopal, Arun Malik, Kausar Yim, Sunghan Stern, Nathan |
author_sort | Baswan, Sudhir M |
collection | PubMed |
description | Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their analogs, have also been associated with the manifestation of dermatological disorders, indicating the effects of the ECS on cutaneous biology. In particular, cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, has garnered significant attention in recent years for its anecdotal therapeutic potential for various pathologies, including skin and cosmetic disorders. Though a body of preclinical evidence suggests topical application of CBD may be efficacious for some skin disorders, such as eczema, psoriasis, pruritis, and inflammatory conditions, confirmed clinical efficacy and elucidation of underlying molecular mechanisms have yet to be fully identified. This article provides an update on the advances in CBD research to date and the potential areas of future exploration. |
format | Online Article Text |
id | pubmed-7736837 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-77368372020-12-16 Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders Baswan, Sudhir M Klosner, Allison E Glynn, Kelly Rajgopal, Arun Malik, Kausar Yim, Sunghan Stern, Nathan Clin Cosmet Investig Dermatol Review Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their analogs, have also been associated with the manifestation of dermatological disorders, indicating the effects of the ECS on cutaneous biology. In particular, cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, has garnered significant attention in recent years for its anecdotal therapeutic potential for various pathologies, including skin and cosmetic disorders. Though a body of preclinical evidence suggests topical application of CBD may be efficacious for some skin disorders, such as eczema, psoriasis, pruritis, and inflammatory conditions, confirmed clinical efficacy and elucidation of underlying molecular mechanisms have yet to be fully identified. This article provides an update on the advances in CBD research to date and the potential areas of future exploration. Dove 2020-12-08 /pmc/articles/PMC7736837/ /pubmed/33335413 http://dx.doi.org/10.2147/CCID.S286411 Text en © 2020 Baswan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Baswan, Sudhir M Klosner, Allison E Glynn, Kelly Rajgopal, Arun Malik, Kausar Yim, Sunghan Stern, Nathan Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title | Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title_full | Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title_fullStr | Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title_full_unstemmed | Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title_short | Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders |
title_sort | therapeutic potential of cannabidiol (cbd) for skin health and disorders |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/ https://www.ncbi.nlm.nih.gov/pubmed/33335413 http://dx.doi.org/10.2147/CCID.S286411 |
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