Hemistepsin A suppresses colorectal cancer growth through inhibiting pyruvate dehydrogenase kinase activity

Most cancer cells primarily produce their energy through a high rate of glycolysis followed by lactic acid fermentation even in the presence of abundant oxygen. Pyruvate dehydrogenase kinase (PDK) 1, an enzyme responsible for aerobic glycolysis via phosphorylating and inactivating pyruvate dehydroge...

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Detalles Bibliográficos
Autores principales: Jin, Ling, Kim, Eun-Yeong, Chung, Tae-Wook, Han, Chang Woo, Park, So Young, Han, Jung Ho, Bae, Sung-Jin, Lee, Jong Rok, Kim, Young Woo, Jang, Se Bok, Ha, Ki-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736850/
https://www.ncbi.nlm.nih.gov/pubmed/33318678
http://dx.doi.org/10.1038/s41598-020-79019-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736850/
https://www.ncbi.nlm.nih.gov/pubmed/33318678
http://dx.doi.org/10.1038/s41598-020-79019-1

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