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Phosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder and frequently exacerbates in postmenopausal women. In NAFLD, the endoplasmic reticulum (ER) plays an important role in lipid metabolism, in which salubrinal is a selective inhibitor of eIF2α de-phosphorylation in response t...

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Detalles Bibliográficos
Autores principales:	Li, Jie, Li, Xinle, Liu, Daquan, Zhang, Shiqi, Tan, Nian, Yokota, Hiroki, Zhang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736876/ https://www.ncbi.nlm.nih.gov/pubmed/33318479 http://dx.doi.org/10.1038/s41419-020-03264-5

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