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Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence

While memory T-cells represent a hallmark of adaptive immunity, little is known about the genetic mechanisms regulating the longevity of memory CD4 T cells. Here, we studied the dynamics of gene expression in antigen specific CD4 T cells during infection, memory differentiation, and long-term surviv...

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Detalles Bibliográficos
Autores principales: Song, Nianbin, Sengupta, Srona, Khoruzhenko, Stanislav, Welsh, Robin A., Kim, AeRyon, Kumar, Mithra R., Sønder, Søren Ulrik, Sidhom, John-William, Zhang, Hao, Jie, Chunfa, Siliciano, Robert F., Sadegh-Nasseri, Scheherazade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737224/
https://www.ncbi.nlm.nih.gov/pubmed/32987276
http://dx.doi.org/10.1016/j.cellimm.2020.104210

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