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Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA

BACKGROUND: The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. METHODS: A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induce...

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Autores principales: Lan, Ming-Chin, Liu, Stanley Yung-Chuan, Lan, Ming-Ying, Huang, Yun-Chen, Huang, Tung-Tsun, Hsu, Yen-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737336/
https://www.ncbi.nlm.nih.gov/pubmed/33317645
http://dx.doi.org/10.1186/s40463-020-00478-7
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author Lan, Ming-Chin
Liu, Stanley Yung-Chuan
Lan, Ming-Ying
Huang, Yun-Chen
Huang, Tung-Tsun
Hsu, Yen-Bin
author_facet Lan, Ming-Chin
Liu, Stanley Yung-Chuan
Lan, Ming-Ying
Huang, Yun-Chen
Huang, Tung-Tsun
Hsu, Yen-Bin
author_sort Lan, Ming-Chin
collection PubMed
description BACKGROUND: The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. METHODS: A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings. RESULTS: Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, p < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency. CONCLUSIONS: Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-77373362020-12-17 Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA Lan, Ming-Chin Liu, Stanley Yung-Chuan Lan, Ming-Ying Huang, Yun-Chen Huang, Tung-Tsun Hsu, Yen-Bin J Otolaryngol Head Neck Surg Original Research Article BACKGROUND: The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. METHODS: A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings. RESULTS: Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, p < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency. CONCLUSIONS: Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2020-12-14 /pmc/articles/PMC7737336/ /pubmed/33317645 http://dx.doi.org/10.1186/s40463-020-00478-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Original Research Article
Lan, Ming-Chin
Liu, Stanley Yung-Chuan
Lan, Ming-Ying
Huang, Yun-Chen
Huang, Tung-Tsun
Hsu, Yen-Bin
Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title_full Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title_fullStr Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title_full_unstemmed Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title_short Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
title_sort role of drug-induced sleep endoscopy in evaluation of positional vs non-positional osa
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737336/
https://www.ncbi.nlm.nih.gov/pubmed/33317645
http://dx.doi.org/10.1186/s40463-020-00478-7
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