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BRAF(V600E) mutation impinges on gut microbial markers defining novel biomarkers for serrated colorectal cancer effective therapies
BACKGROUND: Colorectal cancer (CRC) harboring BRAF(V600E) mutation exhibits low response to conventional therapy and poorest prognosis. Due to the emerging correlation between gut microbiota and CRC carcinogenesis, we investigated in serrated BRAF(V600E) cases the existence of a peculiar fecal micro...
Autores principales: | Trivieri, Nadia, Pracella, Riccardo, Cariglia, Maria Grazia, Panebianco, Concetta, Parrella, Paola, Visioli, Alberto, Giani, Fabrizio, Soriano, Amata Amy, Barile, Chiara, Canistro, Giuseppe, Latiano, Tiziana Pia, Dimitri, Lucia, Bazzocchi, Francesca, Cassano, Dario, Vescovi, Angelo L., Pazienza, Valerio, Binda, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737386/ https://www.ncbi.nlm.nih.gov/pubmed/33317591 http://dx.doi.org/10.1186/s13046-020-01801-w |
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