Hepcidin Is a Reliable Marker of Iron Deficiency Anemia in Newly Diagnosed Patients with Inflammatory Bowel Disease

RESULTS: There was a high statistically significant difference between IBD patients and controls in levels of hepcidin (P < 0.01). Namely, serum hepcidin levels were significantly higher in the control group. There was no statistically significant correlation of serum hepcidin with CRP, Mayo scor...

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Detalles Bibliográficos
Autores principales: Stojkovic Lalosevic, Milica, Toncev, Ljubisa, Stankovic, Sanja, Dragasevic, Sanja, Stojkovic, Stefan, Jovicic, Ivana, Stulic, Milos, Culafic, Djordje, Milovanovic, Tamara, Stojanovic, Marija, Aleksic, Marko, Stjepanovic, Mihailo, Lalosevic, Jovan, Kiurski, Stanimir, Oluic, Branislav, Pavlovic Markovic, Aleksandra, Stojkovic, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737436/
https://www.ncbi.nlm.nih.gov/pubmed/33354248
http://dx.doi.org/10.1155/2020/8523205
Descripción
Sumario:RESULTS: There was a high statistically significant difference between IBD patients and controls in levels of hepcidin (P < 0.01). Namely, serum hepcidin levels were significantly higher in the control group. There was no statistically significant correlation of serum hepcidin with CRP, Mayo score, or CDAI, respectively (P > 0.05). However, we have found a statistically significant negative correlation of sTfR and TIBC with hepcidin (P < 0.01). CONCLUSION: Results of our study suggest that hepcidin is a reliable marker of IDA in patients with IBD, and it could be used in routine clinical practice when determining adequate therapy in these patients.

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