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Ocrelizumab-Induced Severe Colitis

We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.

Detalles Bibliográficos
Autores principales: Lee, Hsing Hwa, Sritharan, Naveen, Bermingham, Daniel, Strey, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737437/
https://www.ncbi.nlm.nih.gov/pubmed/33354373
http://dx.doi.org/10.1155/2020/8858378
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author Lee, Hsing Hwa
Sritharan, Naveen
Bermingham, Daniel
Strey, Gabriela
author_facet Lee, Hsing Hwa
Sritharan, Naveen
Bermingham, Daniel
Strey, Gabriela
author_sort Lee, Hsing Hwa
collection PubMed
description We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.
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spelling pubmed-77374372020-12-21 Ocrelizumab-Induced Severe Colitis Lee, Hsing Hwa Sritharan, Naveen Bermingham, Daniel Strey, Gabriela Case Rep Gastrointest Med Case Report We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis. Hindawi 2020-12-07 /pmc/articles/PMC7737437/ /pubmed/33354373 http://dx.doi.org/10.1155/2020/8858378 Text en Copyright © 2020 Hsing Hwa Lee et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Hsing Hwa
Sritharan, Naveen
Bermingham, Daniel
Strey, Gabriela
Ocrelizumab-Induced Severe Colitis
title Ocrelizumab-Induced Severe Colitis
title_full Ocrelizumab-Induced Severe Colitis
title_fullStr Ocrelizumab-Induced Severe Colitis
title_full_unstemmed Ocrelizumab-Induced Severe Colitis
title_short Ocrelizumab-Induced Severe Colitis
title_sort ocrelizumab-induced severe colitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737437/
https://www.ncbi.nlm.nih.gov/pubmed/33354373
http://dx.doi.org/10.1155/2020/8858378
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