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HIV‐1 infection of CD4 T cells impairs antigen‐specific B cell function

Failures to produce neutralizing antibodies upon HIV‐1 infection result in part from B‐cell dysfunction due to unspecific B‐cell activation. How HIV‐1 affects antigen‐specific B‐cell functions remains elusive. Using an adoptive transfer mouse model and ex vivo HIV infection of human tonsil tissue, w...

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Detalles Bibliográficos
Autores principales:	Kaw, Sheetal, Ananth, Swetha, Tsopoulidis, Nikolaos, Morath, Katharina, Coban, Bahar M, Hohenberger, Ralph, Bulut, Olcay C, Klein, Florian, Stolp, Bettina, Fackler, Oliver T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737609/ https://www.ncbi.nlm.nih.gov/pubmed/33146906 http://dx.doi.org/10.15252/embj.2020105594

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