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Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner

Nuclear lipid droplets (LDs) in hepatocytes are derived from precursors of very-low-density lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory function form nuclear LDs. Here, we show that the inner nuclear membrane (INM) of U2OS cells harbors triglyceride s...

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Detalles Bibliográficos
Autores principales: Sołtysik, Kamil, Ohsaki, Yuki, Tatematsu, Tsuyako, Cheng, Jinglei, Maeda, Asami, Morita, Shin-ya, Fujimoto, Toyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737703/
https://www.ncbi.nlm.nih.gov/pubmed/33315072
http://dx.doi.org/10.1083/jcb.202005026