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The AbDesign computational pipeline for modular backbone assembly and design of binders and enzymes
The functional sites of many protein families are dominated by diverse backbone regions that lack secondary structure (loops) but fold stably into their functionally competent state. Nevertheless, the design of structured loop regions from scratch, especially in functional sites, has met with great...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737780/ https://www.ncbi.nlm.nih.gov/pubmed/33040418 http://dx.doi.org/10.1002/pro.3970 |