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Comparative intra-articular gene transfer of seven adeno-associated virus serotypes reveals that AAV2 mediates the most efficient transduction to mouse arthritic chondrocytes

Osteoarthritis (OA) is the most common arthropathy, characterized by progressive degeneration of the articular cartilage. Currently, there are no disease-modifying approaches for OA treatment. Adeno-associated virus (AAV)-mediated gene therapy has recently become a potential treatment for OA due to...

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Detalles Bibliográficos
Autores principales:	Chen, Quan, Luo, Huan, Zhou, Chengcong, Yu, Huan, Yao, Sai, Fu, Fangda, Seeley, Rebecca, Ji, Xing, Yang, Yanping, Chen, Peifeng, Jin, Hongting, Tong, Peijian, Chen, Di, Wu, Chengliang, Du, Weibin, Ruan, Hongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737971/ https://www.ncbi.nlm.nih.gov/pubmed/33320893 http://dx.doi.org/10.1371/journal.pone.0243359

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