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Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis

Total reflection X-ray fluorescence analysis (TXRF) was used to determine chromium, selenium and bromine concentrations in blood serum samples of 50 patients with parenteral nutrition treatment. The concentrations were measured two times, namely in the first day (I measurement) of the treatment and...

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Autores principales: Pierzak, Monika, Kubala-Kukuś, Aldona, Banaś, Dariusz, Stabrawa, Ilona, Wudarczyk-Moćko, Jolanta, Głuszek, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737982/
https://www.ncbi.nlm.nih.gov/pubmed/33320863
http://dx.doi.org/10.1371/journal.pone.0243492
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author Pierzak, Monika
Kubala-Kukuś, Aldona
Banaś, Dariusz
Stabrawa, Ilona
Wudarczyk-Moćko, Jolanta
Głuszek, Stanisław
author_facet Pierzak, Monika
Kubala-Kukuś, Aldona
Banaś, Dariusz
Stabrawa, Ilona
Wudarczyk-Moćko, Jolanta
Głuszek, Stanisław
author_sort Pierzak, Monika
collection PubMed
description Total reflection X-ray fluorescence analysis (TXRF) was used to determine chromium, selenium and bromine concentrations in blood serum samples of 50 patients with parenteral nutrition treatment. The concentrations were measured two times, namely in the first day (I measurement) of the treatment and the seventh day (II measurement) after the chromium and selenium supplementation. For comparison purposes also serum samples of 50 patients without nutritional disorders, admitted to a planned surgical procedure to remove the gall bladder (cholecystectomy), were analyzed and treated as the control group. Descriptive statistics of measured concentrations of Cr, Se and Br both for the studied and control groups was determined. In order to check the effectiveness of Cr and Se supplementation, the results of the first and seventh day measurements for studied group were statistically compared with each other, with literature reference values and with the results of the control group (two-group comparison). These comparisons indicate the effectiveness of selenium supplementation in the applied treatment procedure. In the case of Cr and Br concentrations no statistically significant differences were observed. We conclude that monitoring of the concentration of the important trace elements in human serum should be standard procedure in parenteral nutrition treatment. In this monitoring the TXRF technique can be successfully used.
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spelling pubmed-77379822021-01-08 Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis Pierzak, Monika Kubala-Kukuś, Aldona Banaś, Dariusz Stabrawa, Ilona Wudarczyk-Moćko, Jolanta Głuszek, Stanisław PLoS One Research Article Total reflection X-ray fluorescence analysis (TXRF) was used to determine chromium, selenium and bromine concentrations in blood serum samples of 50 patients with parenteral nutrition treatment. The concentrations were measured two times, namely in the first day (I measurement) of the treatment and the seventh day (II measurement) after the chromium and selenium supplementation. For comparison purposes also serum samples of 50 patients without nutritional disorders, admitted to a planned surgical procedure to remove the gall bladder (cholecystectomy), were analyzed and treated as the control group. Descriptive statistics of measured concentrations of Cr, Se and Br both for the studied and control groups was determined. In order to check the effectiveness of Cr and Se supplementation, the results of the first and seventh day measurements for studied group were statistically compared with each other, with literature reference values and with the results of the control group (two-group comparison). These comparisons indicate the effectiveness of selenium supplementation in the applied treatment procedure. In the case of Cr and Br concentrations no statistically significant differences were observed. We conclude that monitoring of the concentration of the important trace elements in human serum should be standard procedure in parenteral nutrition treatment. In this monitoring the TXRF technique can be successfully used. Public Library of Science 2020-12-15 /pmc/articles/PMC7737982/ /pubmed/33320863 http://dx.doi.org/10.1371/journal.pone.0243492 Text en © 2020 Pierzak et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Pierzak, Monika
Kubala-Kukuś, Aldona
Banaś, Dariusz
Stabrawa, Ilona
Wudarczyk-Moćko, Jolanta
Głuszek, Stanisław
Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title_full Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title_fullStr Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title_full_unstemmed Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title_short Study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection X-ray fluorescence analysis
title_sort study of chromium, selenium and bromine concentrations in blood serum of patients with parenteral nutrition treatment using total reflection x-ray fluorescence analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737982/
https://www.ncbi.nlm.nih.gov/pubmed/33320863
http://dx.doi.org/10.1371/journal.pone.0243492
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