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Clinical safety and efficacy of neoadjuvant combination chemotherapy of tranilast in advanced esophageal squamous cell carcinoma: Phase I/II study (TNAC)
BACKGROUND: Transient receptor potential vanilloid 2 (TRPV2) was previously shown to play an important role in the maintenance of cancer stem cells, and its specific inhibitor, tranilast, also has potential as a targeted therapeutic agent for esophageal squamous cell carcinoma (ESCC). The present st...
Autores principales: | Shiozaki, Atsushi, Kudou, Michihiro, Fujiwara, Hitoshi, Konishi, Hirotaka, Shimizu, Hiroki, Arita, Tomohiro, Kosuga, Toshiyuki, Yamamoto, Yusuke, Morimura, Ryo, Ikoma, Hisashi, Kuriu, Yoshiaki, Kubota, Takeshi, Okamoto, Kazuma, Otsuji, Eigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738016/ https://www.ncbi.nlm.nih.gov/pubmed/33327342 http://dx.doi.org/10.1097/MD.0000000000023633 |
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