Quantitative dissection of transcription in development yields evidence for transcription-factor-driven chromatin accessibility

Thermodynamic models of gene regulation can predict transcriptional regulation in bacteria, but in eukaryotes, chromatin accessibility and energy expenditure may call for a different framework. Here, we systematically tested the predictive power of models of DNA accessibility based on the Monod-Wyma...

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Detalles Bibliográficos
Autores principales: Eck, Elizabeth, Liu, Jonathan, Kazemzadeh-Atoufi, Maryam, Ghoreishi, Sydney, Blythe, Shelby A, Garcia, Hernan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738189/
https://www.ncbi.nlm.nih.gov/pubmed/33074101
http://dx.doi.org/10.7554/eLife.56429

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