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γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors
Described as the “proteasome of the membrane” or the “scissors in the membrane,” γ-secretase has notoriously complicated biology, and even after decades of research, the full extent of its regulatory mechanism remains unclear. γ-Secretase is an intramembrane aspartyl protease complex composed of fou...
Autores principales: | Wong, Eitan, Frost, Georgia R., Li, Yue-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738330/ https://www.ncbi.nlm.nih.gov/pubmed/33343338 http://dx.doi.org/10.3389/fnagi.2020.614690 |
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