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Foxp3-Positive Regulatory T Cells Contribute to Antifibrotic Effects in Renal Fibrosis via an Interleukin-18 Receptor Signaling Pathway

Renal interstitial fibrosis is a common lesion in the process of various progressive renal diseases. Interleukin (IL)-18 is a proinflammatory cytokine that plays an important role in the induction of Th1 responses and is associated with renal interstitial fibrosis, but the mechanism of fibrosis rema...

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Detalles Bibliográficos
Autores principales: Hirooka, Yasuaki, Nozaki, Yuji, Niki, Kaoru, Inoue, Asuka, Sugiyama, Masafumi, Kinoshita, Koji, Funauchi, Masanori, Matsumura, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738332/
https://www.ncbi.nlm.nih.gov/pubmed/33344483
http://dx.doi.org/10.3389/fmed.2020.604656