Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy

Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality globally. Recent decades have seen the evolution of international collaborations to improve care for these patients and identify areas for research. In this article we discuss the pathophysiology underlyin...

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Autores principales: Lonsdale, Dagan O., Shah, Reya V., Lipman, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738462/
https://www.ncbi.nlm.nih.gov/pubmed/33344475
http://dx.doi.org/10.3389/fmed.2020.588863
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author Lonsdale, Dagan O.
Shah, Reya V.
Lipman, Jeffrey
author_facet Lonsdale, Dagan O.
Shah, Reya V.
Lipman, Jeffrey
author_sort Lonsdale, Dagan O.
collection PubMed
description Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality globally. Recent decades have seen the evolution of international collaborations to improve care for these patients and identify areas for research. In this article we discuss the pathophysiology underlying the condition, review the current recommended management strategies, discuss areas of controversy, and highlight the need for ongoing research, particularly in diagnostics.
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spelling pubmed-77384622020-12-17 Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy Lonsdale, Dagan O. Shah, Reya V. Lipman, Jeffrey Front Med (Lausanne) Medicine Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality globally. Recent decades have seen the evolution of international collaborations to improve care for these patients and identify areas for research. In this article we discuss the pathophysiology underlying the condition, review the current recommended management strategies, discuss areas of controversy, and highlight the need for ongoing research, particularly in diagnostics. Frontiers Media S.A. 2020-12-02 /pmc/articles/PMC7738462/ /pubmed/33344475 http://dx.doi.org/10.3389/fmed.2020.588863 Text en Copyright © 2020 Lonsdale, Shah and Lipman. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Lonsdale, Dagan O.
Shah, Reya V.
Lipman, Jeffrey
Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title_full Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title_fullStr Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title_full_unstemmed Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title_short Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
title_sort infection, sepsis and the inflammatory response: mechanisms and therapy
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738462/
https://www.ncbi.nlm.nih.gov/pubmed/33344475
http://dx.doi.org/10.3389/fmed.2020.588863
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