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Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study

Aims: To evaluate the repeatability of cardiac magnetic resonance (CMR) radiomics features on test-retest scanning using a multi-centre multi-vendor dataset with a varied case-mix. Methods and Results: The sample included 54 test-retest studies from the VOLUMES resource (thevolumesresource.com). Ima...

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Autores principales: Raisi-Estabragh, Zahra, Gkontra, Polyxeni, Jaggi, Akshay, Cooper, Jackie, Augusto, João, Bhuva, Anish N., Davies, Rhodri H., Manisty, Charlotte H., Moon, James C., Munroe, Patricia B., Harvey, Nicholas C., Lekadir, Karim, Petersen, Steffen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738466/
https://www.ncbi.nlm.nih.gov/pubmed/33344517
http://dx.doi.org/10.3389/fcvm.2020.586236
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author Raisi-Estabragh, Zahra
Gkontra, Polyxeni
Jaggi, Akshay
Cooper, Jackie
Augusto, João
Bhuva, Anish N.
Davies, Rhodri H.
Manisty, Charlotte H.
Moon, James C.
Munroe, Patricia B.
Harvey, Nicholas C.
Lekadir, Karim
Petersen, Steffen E.
author_facet Raisi-Estabragh, Zahra
Gkontra, Polyxeni
Jaggi, Akshay
Cooper, Jackie
Augusto, João
Bhuva, Anish N.
Davies, Rhodri H.
Manisty, Charlotte H.
Moon, James C.
Munroe, Patricia B.
Harvey, Nicholas C.
Lekadir, Karim
Petersen, Steffen E.
author_sort Raisi-Estabragh, Zahra
collection PubMed
description Aims: To evaluate the repeatability of cardiac magnetic resonance (CMR) radiomics features on test-retest scanning using a multi-centre multi-vendor dataset with a varied case-mix. Methods and Results: The sample included 54 test-retest studies from the VOLUMES resource (thevolumesresource.com). Images were segmented according to a pre-defined protocol to select three regions of interest (ROI) in end-diastole and end-systole: right ventricle, left ventricle (LV), and LV myocardium. We extracted radiomics shape features from all three ROIs and, additionally, first-order and texture features from the LV myocardium. Overall, 280 features were derived per study. For each feature, we calculated intra-class correlation coefficient (ICC), within-subject coefficient of variation, and mean relative difference. We ranked robustness of features according to mean ICC stratified by feature category, ROI, and cardiac phase, demonstrating a wide range of repeatability. There were features with good and excellent repeatability (ICC ≥ 0.75) within all feature categories and ROIs. A high proportion of first-order and texture features had excellent repeatability (ICC ≥ 0.90), however, these categories also contained features with the poorest repeatability (ICC < 0.50). Conclusion: CMR radiomic features have a wide range of repeatability. This paper is intended as a reference for future researchers to guide selection of the most robust features for clinical CMR radiomics models. Further work in larger and richer datasets is needed to further define the technical performance and clinical utility of CMR radiomics.
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spelling pubmed-77384662020-12-17 Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study Raisi-Estabragh, Zahra Gkontra, Polyxeni Jaggi, Akshay Cooper, Jackie Augusto, João Bhuva, Anish N. Davies, Rhodri H. Manisty, Charlotte H. Moon, James C. Munroe, Patricia B. Harvey, Nicholas C. Lekadir, Karim Petersen, Steffen E. Front Cardiovasc Med Cardiovascular Medicine Aims: To evaluate the repeatability of cardiac magnetic resonance (CMR) radiomics features on test-retest scanning using a multi-centre multi-vendor dataset with a varied case-mix. Methods and Results: The sample included 54 test-retest studies from the VOLUMES resource (thevolumesresource.com). Images were segmented according to a pre-defined protocol to select three regions of interest (ROI) in end-diastole and end-systole: right ventricle, left ventricle (LV), and LV myocardium. We extracted radiomics shape features from all three ROIs and, additionally, first-order and texture features from the LV myocardium. Overall, 280 features were derived per study. For each feature, we calculated intra-class correlation coefficient (ICC), within-subject coefficient of variation, and mean relative difference. We ranked robustness of features according to mean ICC stratified by feature category, ROI, and cardiac phase, demonstrating a wide range of repeatability. There were features with good and excellent repeatability (ICC ≥ 0.75) within all feature categories and ROIs. A high proportion of first-order and texture features had excellent repeatability (ICC ≥ 0.90), however, these categories also contained features with the poorest repeatability (ICC < 0.50). Conclusion: CMR radiomic features have a wide range of repeatability. This paper is intended as a reference for future researchers to guide selection of the most robust features for clinical CMR radiomics models. Further work in larger and richer datasets is needed to further define the technical performance and clinical utility of CMR radiomics. Frontiers Media S.A. 2020-12-02 /pmc/articles/PMC7738466/ /pubmed/33344517 http://dx.doi.org/10.3389/fcvm.2020.586236 Text en Copyright © 2020 Raisi-Estabragh, Gkontra, Jaggi, Cooper, Augusto, Bhuva, Davies, Manisty, Moon, Munroe, Harvey, Lekadir and Petersen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Raisi-Estabragh, Zahra
Gkontra, Polyxeni
Jaggi, Akshay
Cooper, Jackie
Augusto, João
Bhuva, Anish N.
Davies, Rhodri H.
Manisty, Charlotte H.
Moon, James C.
Munroe, Patricia B.
Harvey, Nicholas C.
Lekadir, Karim
Petersen, Steffen E.
Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title_full Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title_fullStr Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title_full_unstemmed Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title_short Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
title_sort repeatability of cardiac magnetic resonance radiomics: a multi-centre multi-vendor test-retest study
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738466/
https://www.ncbi.nlm.nih.gov/pubmed/33344517
http://dx.doi.org/10.3389/fcvm.2020.586236
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