Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2

Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein–protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducib...

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Detalles Bibliográficos
Autores principales: Chowdhury, Rasheduzzaman, Abboud, Martine I., McAllister, Tom E., Banerji, Biswadip, Bhushan, Bhaskar, Sorensen, John L., Kawamura, Akane, Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738489/
https://www.ncbi.nlm.nih.gov/pubmed/33319810
http://dx.doi.org/10.1038/s41598-020-76307-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738489/
https://www.ncbi.nlm.nih.gov/pubmed/33319810
http://dx.doi.org/10.1038/s41598-020-76307-8

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