Cargando…

Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies

Reverse-phase protein array (RPPA) technology uses panels of high-specificity antibodies to measure proteins and protein post-translational modifications in cells and tissues. The approach offers sensitive and precise quantification of large numbers of samples and has thus found applications in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Byron, Adam, Bernhardt, Stephan, Ouine, Bérèngere, Cartier, Aurélie, Macleod, Kenneth G., Carragher, Neil O., Sibut, Vonick, Korf, Ulrike, Serrels, Bryan, de Koning, Leanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738515/ https://www.ncbi.nlm.nih.gov/pubmed/33319783 http://dx.doi.org/10.1038/s41598-020-77335-0

Ejemplares similares

Analysis of Reverse Phase Protein Array Data: From Experimental Design towards Targeted Biomarker Discovery
por: Wachter, Astrid, et al.
Publicado: (2015)

Correction: Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma
por: Lièvre, Astrid, et al.
Publicado: (2018)

Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma
por: Lièvre, Astrid, et al.
Publicado: (2017)

Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array
por: Partolina, Marina, et al.
Publicado: (2017)

Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer in combination to PARP inhibition
por: El Botty, Rania, et al.
Publicado: (2018)

RNAi-based validation of antibodies for reverse phase protein arrays
por: Mannsperger, Heiko A, et al.
Publicado: (2010)

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification
por: Brase, Jan C, et al.
Publicado: (2010)

Identification of differentially expressed genes in chickens differing in muscle glycogen content and meat quality
por: Sibut, Vonick, et al.
Publicado: (2011)

NormaCurve: A SuperCurve-Based Method That Simultaneously Quantifies and Normalizes Reverse Phase Protein Array Data
por: Troncale, Sylvie, et al.
Publicado: (2012)

PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma
por: de Koning, Leanne, et al.
Publicado: (2019)

Gene expression profiling to identify eggshell proteins involved in physical defense of the chicken egg
por: Jonchère, Vincent, et al.
Publicado: (2010)

Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex
por: Chmiest, Daniela, et al.
Publicado: (2016)

Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data
por: Bender, Christian, et al.
Publicado: (2010)

Metabolic transformations in breast cancer subtypes
por: Mitra, Devina, et al.
Publicado: (2014)

Energy Management System for the Train Inspection Monorail
por: Sibut, Leo
Publicado: (2019)

Profiling metabolic changes in breast cancer with targeted proteomics
por: Bernhardt, Stephan, et al.
Publicado: (2014)

Array Platform Modeling and Analysis (A)
por: Qin, Li-Xuan, et al.
Publicado: (2015)

FAK and talin: Who is taking whom to the integrin engagement party?
por: Serrels, Bryan, et al.
Publicado: (2012)

Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib
por: Wind, Sven, et al.
Publicado: (2019)

Pharmacodynamic Material Basis and Potential Mechanism Study of Spatholobi Caulis in Reversing Osteoporosis
por: Xiao, Jianpeng, et al.
Publicado: (2023)

Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts
por: Coussy, Florence, et al.
Publicado: (2020)

Establishment of an AAV Reverse Infection-Based Array
por: Dong, Xiaoyan, et al.
Publicado: (2010)

Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability
por: Usach, Iris, et al.
Publicado: (2013)

Annotation and cross-indexing of array elements on multiple platforms.
por: Mattes, William B
Publicado: (2004)

WebArray: an online platform for microarray data analysis
por: Xia, Xiaoqin, et al.
Publicado: (2005)

CAPweb: a bioinformatics CGH array Analysis Platform
por: Liva, Stéphane, et al.
Publicado: (2006)

Sonochemically Fabricated Microelectrode Arrays for Use as Sensing Platforms
por: Collyer, Stuart D., et al.
Publicado: (2010)

Live Cell in Vitro and in Vivo Imaging Applications: Accelerating Drug Discovery
por: Isherwood, Beverley, et al.
Publicado: (2011)

Disentangling ERBB Signaling in Breast Cancer Subtypes—A Model-Based Analysis
por: Kemmer, Svenja, et al.
Publicado: (2022)

Pharmacokinetics and Pharmacodynamics of the Reverse Transcriptase Inhibitor Tenofovir and Prophylactic Efficacy against HIV-1 Infection
por: Duwal, Sulav, et al.
Publicado: (2012)

Safety, pharmacokinetics, and pharmacodynamics of BMS-986142, a novel reversible BTK inhibitor, in healthy participants
por: Lee, Sun Ku, et al.
Publicado: (2017)

RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
por: Stanislaus, Romesh, et al.
Publicado: (2008)

In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy
por: Lee, Martin, et al.
Publicado: (2015)

Spatial Normalization of Reverse Phase Protein Array Data
por: Kaushik, Poorvi, et al.
Publicado: (2014)

CMU Array: A 3D nanoprinted, fully customizable high-density microelectrode array platform
por: Saleh, Mohammad Sadeq, et al.
Publicado: (2022)

arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
por: Menten, Björn, et al.
Publicado: (2005)

Performance evaluation of commercial miRNA expression array platforms
por: Sah, Sachin, et al.
Publicado: (2010)

A solid‐phase transfection platform for arrayed CRISPR screens
por: Serçin, Özdemirhan, et al.
Publicado: (2019)

Pharmacodynamics in hypothermia
por: Tveita, Torkjel
Publicado: (2012)

Pharmacodynamic Parameters of Pharmacokinetic/Pharmacodynamic (PK/PD) Integration Models
por: Zhang, Longfei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3f9ii360si2j79t34faddabaf3