Differential metabolic responses in breast cancer cell lines to acidosis and lactic acidosis revealed by stable isotope assisted metabolomics

Extracellular acidosis is considered as a hallmark of most human tumors, which plays an important role in promoting tumor malignant and aggressive phenotype in tumorigenesis. Acidosis and lactic acidosis can induce different responses in tumors. Previous studies have associated the response to lacti...

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Detalles Bibliográficos
Autores principales: Gao, Jiayue, Guo, Zhiying, Cheng, Jianhua, Sun, Bo, Yang, Jie, Li, Haijing, Wu, Shengming, Dong, Fangting, Yan, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738541/
https://www.ncbi.nlm.nih.gov/pubmed/33319827
http://dx.doi.org/10.1038/s41598-020-78955-2

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