Discordant Responses Between Primary Head and Neck Tumors and Nodal Metastases Treated With Neoadjuvant Nivolumab: Correlation of Radiographic and Pathologic Treatment Effect

PD-1 blockade represents a promising treatment in patients with head and neck squamous cell carcinoma (HNSCC). We analyzed results of a neoadjuvant randomized window-of-opportunity trial of nivolumab plus/minus tadalafil to investigate whether immunotherapy-mediated treatment effects vary by site of...

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Detalles Bibliográficos
Autores principales: Merlino, Dante J., Johnson, Jennifer M., Tuluc, Madalina, Gargano, Stacey, Stapp, Robert, Harshyne, Larry, Leiby, Benjamin E., Flanders, Adam, Zinner, Ralph, Axelrod, Rita, Curry, Joseph, Cognetti, David M., Mannion, Kyle, Kim, Young J., Rodeck, Ulrich, Argiris, Athanassios, Luginbuhl, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738605/
https://www.ncbi.nlm.nih.gov/pubmed/33344227
http://dx.doi.org/10.3389/fonc.2020.566315

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