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Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
BACKGROUND: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases. METHODS: We asked participants to join our...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Epidemiological Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738642/ https://www.ncbi.nlm.nih.gov/pubmed/31932529 http://dx.doi.org/10.2188/jea.JE20190271 |
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author | Hozawa, Atsushi Tanno, Kozo Nakaya, Naoki Nakamura, Tomohiro Tsuchiya, Naho Hirata, Takumi Narita, Akira Kogure, Mana Nochioka, Kotaro Sasaki, Ryohei Takanashi, Nobuyuki Otsuka, Kotaro Sakata, Kiyomi Kuriyama, Shinichi Kikuya, Masahiro Tanabe, Osamu Sugawara, Junichi Suzuki, Kichiya Suzuki, Yoichi Kodama, Eiichi N Fuse, Nobuo Kiyomoto, Hideyasu Tomita, Hiroaki Uruno, Akira Hamanaka, Yohei Metoki, Hirohito Ishikuro, Mami Obara, Taku Kobayashi, Tomoko Kitatani, Kazuyuki Takai-Igarashi, Takako Ogishima, Soichi Satoh, Mamoru Ohmomo, Hideki Tsuboi, Akito Egawa, Shinichi Ishii, Tadashi Ito, Kiyoshi Ito, Sadayoshi Taki, Yasuyuki Minegishi, Naoko Ishii, Naoto Nagasaki, Masao Igarashi, Kazuhiko Koshiba, Seizo Shimizu, Ritsuko Tamiya, Gen Nakayama, Keiko Motohashi, Hozumi Yasuda, Jun Shimizu, Atsushi Hachiya, Tsuyoshi Shiwa, Yuh Tominaga, Teiji Tanaka, Hiroshi Oyama, Kotaro Tanaka, Ryoichi Kawame, Hiroshi Fukushima, Akimune Ishigaki, Yasushi Tokutomi, Tomoharu Osumi, Noriko Kobayashi, Tadao Nagami, Fuji Hashizume, Hiroaki Arai, Tomohiko Kawaguchi, Yoshio Higuchi, Shinichi Sakaida, Masaki Endo, Ryujin Nishizuka, Satoshi Tsuji, Ichiro Hitomi, Jiro Nakamura, Motoyuki Ogasawara, Kuniaki Yaegashi, Nobuo Kinoshita, Kengo Kure, Shigeo Sakai, Akio Kobayashi, Seiichiro Sobue, Kenji Sasaki, Makoto Yamamoto, Masayuki |
author_facet | Hozawa, Atsushi Tanno, Kozo Nakaya, Naoki Nakamura, Tomohiro Tsuchiya, Naho Hirata, Takumi Narita, Akira Kogure, Mana Nochioka, Kotaro Sasaki, Ryohei Takanashi, Nobuyuki Otsuka, Kotaro Sakata, Kiyomi Kuriyama, Shinichi Kikuya, Masahiro Tanabe, Osamu Sugawara, Junichi Suzuki, Kichiya Suzuki, Yoichi Kodama, Eiichi N Fuse, Nobuo Kiyomoto, Hideyasu Tomita, Hiroaki Uruno, Akira Hamanaka, Yohei Metoki, Hirohito Ishikuro, Mami Obara, Taku Kobayashi, Tomoko Kitatani, Kazuyuki Takai-Igarashi, Takako Ogishima, Soichi Satoh, Mamoru Ohmomo, Hideki Tsuboi, Akito Egawa, Shinichi Ishii, Tadashi Ito, Kiyoshi Ito, Sadayoshi Taki, Yasuyuki Minegishi, Naoko Ishii, Naoto Nagasaki, Masao Igarashi, Kazuhiko Koshiba, Seizo Shimizu, Ritsuko Tamiya, Gen Nakayama, Keiko Motohashi, Hozumi Yasuda, Jun Shimizu, Atsushi Hachiya, Tsuyoshi Shiwa, Yuh Tominaga, Teiji Tanaka, Hiroshi Oyama, Kotaro Tanaka, Ryoichi Kawame, Hiroshi Fukushima, Akimune Ishigaki, Yasushi Tokutomi, Tomoharu Osumi, Noriko Kobayashi, Tadao Nagami, Fuji Hashizume, Hiroaki Arai, Tomohiko Kawaguchi, Yoshio Higuchi, Shinichi Sakaida, Masaki Endo, Ryujin Nishizuka, Satoshi Tsuji, Ichiro Hitomi, Jiro Nakamura, Motoyuki Ogasawara, Kuniaki Yaegashi, Nobuo Kinoshita, Kengo Kure, Shigeo Sakai, Akio Kobayashi, Seiichiro Sobue, Kenji Sasaki, Makoto Yamamoto, Masayuki |
author_sort | Hozawa, Atsushi |
collection | PubMed |
description | BACKGROUND: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases. METHODS: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely. RESULTS: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex. CONCLUSION: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information. |
format | Online Article Text |
id | pubmed-7738642 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Japan Epidemiological Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-77386422021-01-05 Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study Hozawa, Atsushi Tanno, Kozo Nakaya, Naoki Nakamura, Tomohiro Tsuchiya, Naho Hirata, Takumi Narita, Akira Kogure, Mana Nochioka, Kotaro Sasaki, Ryohei Takanashi, Nobuyuki Otsuka, Kotaro Sakata, Kiyomi Kuriyama, Shinichi Kikuya, Masahiro Tanabe, Osamu Sugawara, Junichi Suzuki, Kichiya Suzuki, Yoichi Kodama, Eiichi N Fuse, Nobuo Kiyomoto, Hideyasu Tomita, Hiroaki Uruno, Akira Hamanaka, Yohei Metoki, Hirohito Ishikuro, Mami Obara, Taku Kobayashi, Tomoko Kitatani, Kazuyuki Takai-Igarashi, Takako Ogishima, Soichi Satoh, Mamoru Ohmomo, Hideki Tsuboi, Akito Egawa, Shinichi Ishii, Tadashi Ito, Kiyoshi Ito, Sadayoshi Taki, Yasuyuki Minegishi, Naoko Ishii, Naoto Nagasaki, Masao Igarashi, Kazuhiko Koshiba, Seizo Shimizu, Ritsuko Tamiya, Gen Nakayama, Keiko Motohashi, Hozumi Yasuda, Jun Shimizu, Atsushi Hachiya, Tsuyoshi Shiwa, Yuh Tominaga, Teiji Tanaka, Hiroshi Oyama, Kotaro Tanaka, Ryoichi Kawame, Hiroshi Fukushima, Akimune Ishigaki, Yasushi Tokutomi, Tomoharu Osumi, Noriko Kobayashi, Tadao Nagami, Fuji Hashizume, Hiroaki Arai, Tomohiko Kawaguchi, Yoshio Higuchi, Shinichi Sakaida, Masaki Endo, Ryujin Nishizuka, Satoshi Tsuji, Ichiro Hitomi, Jiro Nakamura, Motoyuki Ogasawara, Kuniaki Yaegashi, Nobuo Kinoshita, Kengo Kure, Shigeo Sakai, Akio Kobayashi, Seiichiro Sobue, Kenji Sasaki, Makoto Yamamoto, Masayuki J Epidemiol Study Profile BACKGROUND: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases. METHODS: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely. RESULTS: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex. CONCLUSION: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information. Japan Epidemiological Association 2021-01-05 /pmc/articles/PMC7738642/ /pubmed/31932529 http://dx.doi.org/10.2188/jea.JE20190271 Text en © 2020 Atsushi Hozawa et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Study Profile Hozawa, Atsushi Tanno, Kozo Nakaya, Naoki Nakamura, Tomohiro Tsuchiya, Naho Hirata, Takumi Narita, Akira Kogure, Mana Nochioka, Kotaro Sasaki, Ryohei Takanashi, Nobuyuki Otsuka, Kotaro Sakata, Kiyomi Kuriyama, Shinichi Kikuya, Masahiro Tanabe, Osamu Sugawara, Junichi Suzuki, Kichiya Suzuki, Yoichi Kodama, Eiichi N Fuse, Nobuo Kiyomoto, Hideyasu Tomita, Hiroaki Uruno, Akira Hamanaka, Yohei Metoki, Hirohito Ishikuro, Mami Obara, Taku Kobayashi, Tomoko Kitatani, Kazuyuki Takai-Igarashi, Takako Ogishima, Soichi Satoh, Mamoru Ohmomo, Hideki Tsuboi, Akito Egawa, Shinichi Ishii, Tadashi Ito, Kiyoshi Ito, Sadayoshi Taki, Yasuyuki Minegishi, Naoko Ishii, Naoto Nagasaki, Masao Igarashi, Kazuhiko Koshiba, Seizo Shimizu, Ritsuko Tamiya, Gen Nakayama, Keiko Motohashi, Hozumi Yasuda, Jun Shimizu, Atsushi Hachiya, Tsuyoshi Shiwa, Yuh Tominaga, Teiji Tanaka, Hiroshi Oyama, Kotaro Tanaka, Ryoichi Kawame, Hiroshi Fukushima, Akimune Ishigaki, Yasushi Tokutomi, Tomoharu Osumi, Noriko Kobayashi, Tadao Nagami, Fuji Hashizume, Hiroaki Arai, Tomohiko Kawaguchi, Yoshio Higuchi, Shinichi Sakaida, Masaki Endo, Ryujin Nishizuka, Satoshi Tsuji, Ichiro Hitomi, Jiro Nakamura, Motoyuki Ogasawara, Kuniaki Yaegashi, Nobuo Kinoshita, Kengo Kure, Shigeo Sakai, Akio Kobayashi, Seiichiro Sobue, Kenji Sasaki, Makoto Yamamoto, Masayuki Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title | Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title_full | Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title_fullStr | Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title_full_unstemmed | Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title_short | Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study |
title_sort | study profile of the tohoku medical megabank community-based cohort study |
topic | Study Profile |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738642/ https://www.ncbi.nlm.nih.gov/pubmed/31932529 http://dx.doi.org/10.2188/jea.JE20190271 |
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