Multiplexed gene expression analysis of HLA class II-associated podoconiosis implicates chronic immune activation in its pathogenesis

BACKGROUND: Podoconiosis is a tropical lymphoedema of the leg resulting from barefoot exposure to irritant volcanic soils. Approximately 4 million people are affected, mainly in African highland regions. The pathogenesis of this neglected tropical disease is still largely unknown, although HLA class...

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Detalles Bibliográficos
Autores principales: Alcantara, Diana R, Jones, Christopher I, Altmann, Daniel M, Boyton, Rosemary J, Haniffa, Muzlifah, Newport, Melanie J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738654/
https://www.ncbi.nlm.nih.gov/pubmed/33099652
http://dx.doi.org/10.1093/trstmh/traa107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738654/
https://www.ncbi.nlm.nih.gov/pubmed/33099652
http://dx.doi.org/10.1093/trstmh/traa107

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