Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts

BACKGROUND: While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. METHODS: We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health...

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Detalles Bibliográficos
Autores principales: Masraf, Hannah, Azemeraw, Temesgen, Molla, Meseret, Jones, Christopher Iain, Bremner, Stephen, Ngari, Moses, Berkley, James A, Kivaya, Esther, Fegan, Greg, Tamiru, Abreham, Kelemework, Abebe, Lang, Trudie, Newport, Melanie J, Davey, Gail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738655/
https://www.ncbi.nlm.nih.gov/pubmed/33236119
http://dx.doi.org/10.1093/trstmh/traa150
Descripción
Sumario:BACKGROUND: While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. METHODS: We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort. RESULTS: The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4). CONCLUSIONS: Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.

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