Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity

Runt-related transcription factor 2 (RUNX2) is critical for the development of the vertebrate bony skeleton. Unlike other RUNX family members, RUNX2 possesses a variable poly-glutamine, poly-alanine (QA) repeat domain. Natural variation within this repeat is able to alter the transactivation potenti...

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Detalles Bibliográficos
Autores principales: Newton, Axel H., Pask, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738678/
https://www.ncbi.nlm.nih.gov/pubmed/33319865
http://dx.doi.org/10.1038/s42003-020-01501-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738678/
https://www.ncbi.nlm.nih.gov/pubmed/33319865
http://dx.doi.org/10.1038/s42003-020-01501-3

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