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Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity
Runt-related transcription factor 2 (RUNX2) is critical for the development of the vertebrate bony skeleton. Unlike other RUNX family members, RUNX2 possesses a variable poly-glutamine, poly-alanine (QA) repeat domain. Natural variation within this repeat is able to alter the transactivation potenti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738678/ https://www.ncbi.nlm.nih.gov/pubmed/33319865 http://dx.doi.org/10.1038/s42003-020-01501-3 |