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Tamoxifen and its metabolites induce mitochondrial membrane depolarization and caspase‐3 activation in equine neutrophils

Neutrophils participate in innate immunity as the first line of host defence against microorganisms. However, persistent neutrophil activity and delayed apoptosis can be harmful to surrounding tissues; this problem occurs in diverse inflammatory diseases, including asthma‐affected horses. Previous s...

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Detalles Bibliográficos
Autores principales: Albornoz, Alejandro, Morales, Natalia, Uberti, Benjamin, Henriquez, Claudio, Burgos, Rafael A., Alarcon, Pablo, Moran, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738725/
https://www.ncbi.nlm.nih.gov/pubmed/32558352
http://dx.doi.org/10.1002/vms3.316