Cargando…

Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-α Expression in Primary Rat Microglia

The activation of microglial cells plays an important role in the cascade of events leading to inflammation-mediated neurodegenerative disorders. Precision therapeutics require that adjunctively feasible drugs be found to prevent microglial cell activation and prevent inflammation-mediated neuronal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yung-Ning, Yang, Yu-Chen S. H., Wu, Pei-Ling, Yang, Chun-Hwa, Kuo, Kuang-Che, Yang, San-Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738791/ https://www.ncbi.nlm.nih.gov/pubmed/33376453 http://dx.doi.org/10.1155/2020/9694012

Ejemplares similares

Granulocyte Colony-Stimulating Factor Alleviates Bacterial-Induced Neuronal Apoptotic Damage in the Neonatal Rat Brain through Epigenetic Histone Modification
por: Yang, Yung-Ning, et al.
Publicado: (2018)

Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice
por: Yang, Pao-Pao, et al.
Publicado: (2015)

Dextromethorphan Inhibits Activations and Functions in Dendritic Cells
por: Chen, Der-Yuan, et al.
Publicado: (2013)

Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder
por: Lu, Ru-Band, et al.
Publicado: (2020)

Enhanced H3K4 Trimethylation in TNF-α Promoter Gene Locus with Cell Apoptosis in the Ventral-Medial Striatum following Opioid Withdrawal of Neonatal Rat Offspring from Morphine-Addicted Mothers
por: Wu, Pei-Ling, et al.
Publicado: (2021)

Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
por: Zhang, Xiong, et al.
Publicado: (2020)

A Placebo-Controlled Trial of Dextromethorphan as an Adjunct in Opioid-Dependent Patients Undergoing Methadone Maintenance Treatment
por: Lee, Sheng-Yu, et al.
Publicado: (2015)

Dextromethorphan Attenuates Sensorineural Hearing Loss in an Animal Model and Population-Based Cohort Study
por: Chen, Hsin-Chien, et al.
Publicado: (2020)

Deuterated dextromethorphan/quinidine for agitation in Alzheimer's disease
por: Khoury, Rita
Publicado: (2021)

Antipsychotic Drugs Efficacy in Dextromethorphan-Induced Psychosis
por: Zaremba, Malgorzata, et al.
Publicado: (2023)

Bilateral nephrolithiasis following ingestion of guaifenesin and dextromethorphan
por: Kim, Elizabeth, et al.
Publicado: (2023)

Two Cases of Dextromethorphan Overdose Reversed by Naloxone
por: Kumar, Dhruva, et al.
Publicado: (2023)

Antineuroinflammatory and Neuroprotective Effects of Gyejibokryeong-Hwan in Lipopolysaccharide-Stimulated BV2 Microglia
por: Park, Bo-Kyung, et al.
Publicado: (2019)

Combination of dextromethorphan and memantine in treating bipolar spectrum disorder: a 12-week double-blind randomized clinical trial
por: Lee, Sheng-Yu, et al.
Publicado: (2020)

EP2-PKA signaling is suppressed by triptolide in lipopolysaccharide-induced microglia activation
por: Zhang, Ting, et al.
Publicado: (2015)

Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD
por: Chuang, Wei-Chen, et al.
Publicado: (2019)

Signs & Symptoms of Dextromethorphan Exposure from YouTube
por: Chary, Michael, et al.
Publicado: (2014)

“Robo-Tripping”: Dextromethorphan Abuse and its Anesthetic Implications
por: Linn, Kelly A, et al.
Publicado: (2014)

Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites
por: Su, Wen-Lin, et al.
Publicado: (2019)

Evidence for using dextromethorphan-quinidine for the treatment of agitation in dementia
por: Tampi, Rajesh R, et al.
Publicado: (2020)

Dextromethorphan-bupropion (Auvelity) for the Treatment of Major Depressive Disorder
por: McCarthy, Brian, et al.
Publicado: (2023)

Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation
por: Ye, Xiaoxia, et al.
Publicado: (2020)

Evaluation of the neuroprotective effect of dextromethorphan in the acute phase of ischaemic stroke
por: Mousavi, Seyed Ali, et al.
Publicado: (2011)

Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect
por: Schoedel, Kerri A, et al.
Publicado: (2014)

Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan
por: Nguyen, Linda, et al.
Publicado: (2014)

The Effect of Intrathecal Injection of Dextromethorphan on the Experimental Neuropathic Pain Model
por: Fahmi, Achmad, et al.
Publicado: (2021)

Dextromethorphan Reduces Oxidative Stress and Inhibits Uremic Artery Calcification
por: Liu, En-Shao, et al.
Publicado: (2021)

Dextromethorphan improved cyclosporine-induced depression in mice model of despair
por: Mesripour, Azadeh, et al.
Publicado: (2020)

Dextromethorphan/quinidine for the treatment of bulbar impairment in amyotrophic lateral sclerosis
por: Tabor Gray, Lauren, et al.
Publicado: (2023)

α-Tocopherol Protects Lipopolysaccharide-Activated BV2 Microglia
por: La Torre, Maria Ester, et al.
Publicado: (2023)

Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels
por: Jose, Shinsmon, et al.
Publicado: (2014)

Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia
por: Ngu, Ee-Ling, et al.
Publicado: (2022)

Cyclooxygenase‑2 contributes to the hypoxia‑induced aggravation of the neuroinflammation response stimulated by lipopolysaccharide in microglia
por: Yang, Yifan, et al.
Publicado: (2023)

Spectrophotometric Determination of Pipazethate HCl and Dextromethorphan HBr using Potassium Permanganate
por: Gouda, Ayman Abou El-Fetouh, et al.
Publicado: (2008)

Ovariectomy ameliorates dextromethorphan - induced memory impairment in young female rats
por: Jahng, Jeong Won, et al.
Publicado: (2006)

Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring
por: Chiang, Yao-Chang, et al.
Publicado: (2015)

Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment
por: Chen, Liv Weichien, et al.
Publicado: (2018)

Dextromethorphan and memantine after ketamine analgesia: a randomized control trial
por: Martin, Elodie, et al.
Publicado: (2019)

Alterations in the biochemical indices in Wistar rats exposed to an overdose of codeine and dextromethorphan
por: Kayode, Abolanle A., et al.
Publicado: (2021)

Comparative Evaluation of Preemptive Analgesia of Dextromethorphan and Ibuprofen in Third Molar Surgeries
por: Kale, Saurabh Gajanan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_foesuk2abets4842l2og62m2kk