Cargando…
Adverse Effects of Low‐Dose Methotrexate in a Randomized Double‐Blind Placebo‐Controlled Trial: Adjudicated Hematologic and Skin Cancer Outcomes in the Cardiovascular Inflammation Reduction Trial
OBJECTIVE: Low‐dose methotrexate (LD‐MTX), a cornerstone in the treatment of rheumatoid arthritis, is associated with a moderately increased risk of anemia, leukopenia, and skin cancers, but the risks of myelosuppression and malignancy during LD‐MTX use remain incompletely described. We examined the...
Autores principales: | Vanni, Kathleen M.M., Berliner, Nancy, Paynter, Nina P., Glynn, Robert J., MacFadyen, Jean, Colls, Joshua, Lu, Fengxin, Xu, Chang, Ridker, Paul M., Solomon, Daniel H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738806/ https://www.ncbi.nlm.nih.gov/pubmed/33201596 http://dx.doi.org/10.1002/acr2.11187 |
Ejemplares similares
-
Testing the Effects of Disease‐Modifying Antirheumatic Drugs on Vascular Inflammation in Rheumatoid Arthritis: Rationale and Design of the TARGET Trial
por: Giles, Jon T., et al.
Publicado: (2021) -
Reducing cardiovascular risk with immunomodulators: a randomised active comparator trial among patients with rheumatoid arthritis
por: Solomon, Daniel H, et al.
Publicado: (2023) -
A randomized placebo-controlled trial of methotrexate in psoriatic arthritis
por: Kingsley, Gabrielle H., et al.
Publicado: (2012) -
Effects of Interleukin-1β Inhibition on Blood Pressure, Incident Hypertension, and Residual Inflammatory Risk: A Secondary Analysis of CANTOS
por: Rothman, Alexander MK, et al.
Publicado: (2020) -
A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol
por: May, James, et al.
Publicado: (2018)