Emerging roles of MiR-133a in human cancers

MicroRNAs (miRNAs) can post-transcriptionally regulate the expression of cancer-relevant genes via binding to the 3'-untranslated region (3'-UTR) of the target mRNAs. MiR-133a, as a miRNA, participate in tumorigenesis, progression, autophagy and drug-resistance in various malignancies. Bas...

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Detalles Bibliográficos
Autores principales: Hua, Yu-Ting, Xu, Wen-Xiu, Li, Hui, Xia, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738817/
https://www.ncbi.nlm.nih.gov/pubmed/33391416
http://dx.doi.org/10.7150/jca.48769
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author Hua, Yu-Ting
Xu, Wen-Xiu
Li, Hui
Xia, Min
author_facet Hua, Yu-Ting
Xu, Wen-Xiu
Li, Hui
Xia, Min
author_sort Hua, Yu-Ting
collection PubMed
description MicroRNAs (miRNAs) can post-transcriptionally regulate the expression of cancer-relevant genes via binding to the 3'-untranslated region (3'-UTR) of the target mRNAs. MiR-133a, as a miRNA, participate in tumorigenesis, progression, autophagy and drug-resistance in various malignancies. Based on the recent insights, we discuss the functions of miR-133a in physiological and pathological processes and its potential effects on cancer diagnosis, prognosis and therapy.
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spelling pubmed-77388172021-01-01 Emerging roles of MiR-133a in human cancers Hua, Yu-Ting Xu, Wen-Xiu Li, Hui Xia, Min J Cancer Research Paper MicroRNAs (miRNAs) can post-transcriptionally regulate the expression of cancer-relevant genes via binding to the 3'-untranslated region (3'-UTR) of the target mRNAs. MiR-133a, as a miRNA, participate in tumorigenesis, progression, autophagy and drug-resistance in various malignancies. Based on the recent insights, we discuss the functions of miR-133a in physiological and pathological processes and its potential effects on cancer diagnosis, prognosis and therapy. Ivyspring International Publisher 2021-01-01 /pmc/articles/PMC7738817/ /pubmed/33391416 http://dx.doi.org/10.7150/jca.48769 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Hua, Yu-Ting
Xu, Wen-Xiu
Li, Hui
Xia, Min
Emerging roles of MiR-133a in human cancers
title Emerging roles of MiR-133a in human cancers
title_full Emerging roles of MiR-133a in human cancers
title_fullStr Emerging roles of MiR-133a in human cancers
title_full_unstemmed Emerging roles of MiR-133a in human cancers
title_short Emerging roles of MiR-133a in human cancers
title_sort emerging roles of mir-133a in human cancers
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738817/
https://www.ncbi.nlm.nih.gov/pubmed/33391416
http://dx.doi.org/10.7150/jca.48769
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