Collagenase IV and clusterin-modified polycaprolactone-polyethylene glycol nanoparticles for penetrating dense tumor tissues

Purpose: Novel collagenase IV (ColIV) and clusterin (CLU)-modified polycaprolactone-polyethylene glycol (PCL-PEG) nanoparticles that load doxorubicin (DOX) were designed and fully evaluated in vitro and in vivo. Methods: PCL-PEG-ColIV was synthesized by linking PCL-PEG and ColIV through a carbodiimi...

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Detalles Bibliográficos
Autores principales: Huang, Hao-Yan, Chen, Li-Qing, Sun, Wei, Du, Huan-Huan, Dong, Shunli, Ahmed, Atef Mohammed Qasem, Cao, Dingyun, Cui, Jing-Hao, Zhang, Yi, Cao, Qing-Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738847/
https://www.ncbi.nlm.nih.gov/pubmed/33391512
http://dx.doi.org/10.7150/thno.47446

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