Cytosolic Ca(2+) transients during pulsed focused ultrasound generate reactive oxygen species and cause DNA damage in tumor cells

Mechanical forces from non-ablative pulsed focused ultrasound (pFUS) generate pro-inflammatory tumor microenvironments (TME), marked by increased cytokines, chemokines, and trophic factors, as well as immune cell infiltration and reduced tumor growth. pFUS also causes DNA damage within tumors, which...

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Detalles Bibliográficos
Autores principales: Rosenblatt, Robert B., Frank, Joseph A., Burks, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738866/
https://www.ncbi.nlm.nih.gov/pubmed/33391495
http://dx.doi.org/10.7150/thno.48353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738866/
https://www.ncbi.nlm.nih.gov/pubmed/33391495
http://dx.doi.org/10.7150/thno.48353

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