Cargando…
Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer
Arachidonic acid (AA) is a polyunsaturated fatty acid present at high concentrations in the ovarian cancer (OC) microenvironment and associated with a poor clinical outcome. In the present study, we have unraveled a potential link between AA and macrophage functions. Methods: AA-triggered signal tra...
Autores principales: | Dietze, Raimund, Hammoud, Mohamad K., Gómez-Serrano, María, Unger, Annika, Bieringer, Tim, Finkernagel, Florian, Sokol, Anna M., Nist, Andrea, Stiewe, Thorsten, Reinartz, Silke, Ponath, Viviane, Preußer, Christian, von Strandmann, Elke Pogge, Müller-Brüsselbach, Sabine, Graumann, Johannes, Müller, Rolf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738879/ https://www.ncbi.nlm.nih.gov/pubmed/33391540 http://dx.doi.org/10.7150/thno.52442 |
Ejemplares similares
-
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures
por: Hammoud, Mohamad K., et al.
Publicado: (2022) -
The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis
por: Ojasalu, Kaire, et al.
Publicado: (2023) -
The multicellular signalling network of ovarian cancer metastases
por: Sommerfeld, Leah, et al.
Publicado: (2021) -
Beyond the Extracellular Vesicles: Technical Hurdles, Achieved Goals and Current Challenges When Working on Adipose Cells
por: Gómez-Serrano, María, et al.
Publicado: (2021) -
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization
por: Finkernagel, Florian, et al.
Publicado: (2016)