The 14-3-3σ protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway

Resistance to anoikis, cell death due to matrix detachment, is acquired during tumor progression. The 14-3-3σ protein is implicated in the development of chemo- and radiation resistance, indicating a poor prognosis in multiple human cancers. However, its function in anoikis resistance and metastasis...

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Detalles Bibliográficos
Autores principales: Song, Jia, Liu, Yachong, Liu, Furong, Zhang, Lu, Li, Ganxun, Yuan, Chaoyi, Yu, Chengpeng, Lu, Xun, Liu, Qiumeng, Chen, Xiaoping, Liang, Huifang, Ding, Zeyang, Zhang, Bixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738881/
https://www.ncbi.nlm.nih.gov/pubmed/33391517
http://dx.doi.org/10.7150/thno.51646

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