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Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis

Rationale: Maladaptive cardiac remodeling is a critical step in the progression of heart failure. Low-density lipoprotein receptor-related protein 6 (LRP6), a co-receptor of Wnt, has been implicated in cardiac protection. We aimed to study the role of cardiomyocyte-expressed LRP6 in cardiac remodeli...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Zou, Yan, Chen, Zhidan, Li, Yang, Pan, Le, Wang, Ying, Liu, Ming, Yin, Chao, Wu, Jian, Yang, Chunjie, Zhang, Lei, Li, Chenze, Huang, Zheyong, Wang, Daowen, Qian, Juying, Ge, Junbo, Zou, Yunzeng, Gong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738902/
https://www.ncbi.nlm.nih.gov/pubmed/33391533
http://dx.doi.org/10.7150/thno.48787