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Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study

Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary lifestyle prior to transplantation. This study aimed to evaluate the impact of unsupervised intervention...

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Autores principales: Orlandi, Goffredo, Sofi, Francesco, Moscarelli, Luciano, Cirami, Lino, Mancini, Sabrina, Stefani, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739256/
https://www.ncbi.nlm.nih.gov/pubmed/33467226
http://dx.doi.org/10.3390/jfmk5010010
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author Orlandi, Goffredo
Sofi, Francesco
Moscarelli, Luciano
Cirami, Lino
Mancini, Sabrina
Stefani, Laura
author_facet Orlandi, Goffredo
Sofi, Francesco
Moscarelli, Luciano
Cirami, Lino
Mancini, Sabrina
Stefani, Laura
author_sort Orlandi, Goffredo
collection PubMed
description Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary lifestyle prior to transplantation. This study aimed to evaluate the impact of unsupervised intervention in a tailored home-based aerobic resistance exercise program, based on the anthropometric and cardiovascular parameters in a group of renal transplant recipients (RTRs) followed for 12 months. Methods: a group of 21 RTRs (mean age: 46.8 ± 12 years) were enrolled in a combined aerobic and step count unsupervised prescription program. Body composition (BMI, waist circumferences, skin-folds); water distribution (TBW: Total body water; ECW: Extra cellular water; and ICW: Intracellular water) and myocardial function were measured every 6 months for 1 year. The MEDI-LITE score was used to estimate adherence to the Mediterranean diet. Results: Significant reductions in waist circumference (Waist Cir: 89.12 ± 12.8 cm T0; 89.1 ± 12.5 cm T6 (95% CI: 6.3, 5.7); 88.6 ± 11.4 cm T12; (95% CI: 6.7, 4.7) p < 0.01), weight:71.8 ± 14.8 kg T0; 70.6 ± 14.7 kg T6(95% CI:−8, 6); 70.6 ± 14.7 kg T12(95% CI: 6.6, 7) p < 0.05), as well as an improvement of myocardial function, as shown by the significant increase of contractility and change in the GLS % value (−18.3 ± 3.8% at T0 (95% CI:−16.57, 20.0.2)−20.4 ± 3.0% at T6(95% CI:−4, 0.2);−22.9 ± 3.1%T12(95% CI:−3, 4, −1, 6) p < 0.02), were observed. Adherence to the Mediterranean diet was in the normal range. Conclusions: Despite unsupervised intervention, combined moderate physical exercise appears to have a positive effect on the main parameters related to cardiovascular risk factors. The long-term efficacy of this program requires further investigation, particularly for evaluating constant adherence to the home-based physical exercise program.
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spelling pubmed-77392562021-01-13 Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study Orlandi, Goffredo Sofi, Francesco Moscarelli, Luciano Cirami, Lino Mancini, Sabrina Stefani, Laura J Funct Morphol Kinesiol Article Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary lifestyle prior to transplantation. This study aimed to evaluate the impact of unsupervised intervention in a tailored home-based aerobic resistance exercise program, based on the anthropometric and cardiovascular parameters in a group of renal transplant recipients (RTRs) followed for 12 months. Methods: a group of 21 RTRs (mean age: 46.8 ± 12 years) were enrolled in a combined aerobic and step count unsupervised prescription program. Body composition (BMI, waist circumferences, skin-folds); water distribution (TBW: Total body water; ECW: Extra cellular water; and ICW: Intracellular water) and myocardial function were measured every 6 months for 1 year. The MEDI-LITE score was used to estimate adherence to the Mediterranean diet. Results: Significant reductions in waist circumference (Waist Cir: 89.12 ± 12.8 cm T0; 89.1 ± 12.5 cm T6 (95% CI: 6.3, 5.7); 88.6 ± 11.4 cm T12; (95% CI: 6.7, 4.7) p < 0.01), weight:71.8 ± 14.8 kg T0; 70.6 ± 14.7 kg T6(95% CI:−8, 6); 70.6 ± 14.7 kg T12(95% CI: 6.6, 7) p < 0.05), as well as an improvement of myocardial function, as shown by the significant increase of contractility and change in the GLS % value (−18.3 ± 3.8% at T0 (95% CI:−16.57, 20.0.2)−20.4 ± 3.0% at T6(95% CI:−4, 0.2);−22.9 ± 3.1%T12(95% CI:−3, 4, −1, 6) p < 0.02), were observed. Adherence to the Mediterranean diet was in the normal range. Conclusions: Despite unsupervised intervention, combined moderate physical exercise appears to have a positive effect on the main parameters related to cardiovascular risk factors. The long-term efficacy of this program requires further investigation, particularly for evaluating constant adherence to the home-based physical exercise program. MDPI 2020-01-30 /pmc/articles/PMC7739256/ /pubmed/33467226 http://dx.doi.org/10.3390/jfmk5010010 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Orlandi, Goffredo
Sofi, Francesco
Moscarelli, Luciano
Cirami, Lino
Mancini, Sabrina
Stefani, Laura
Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title_full Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title_fullStr Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title_full_unstemmed Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title_short Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study
title_sort exercise prescription in renal transplant recipients: from sports medicine toward multidisciplinary aspects: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739256/
https://www.ncbi.nlm.nih.gov/pubmed/33467226
http://dx.doi.org/10.3390/jfmk5010010
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