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No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease

Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, incl...

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Autores principales: Lertthammakiat, Surapong, Sitthirat, Peerasit, Anurathapan, Usanarat, Songdej, Duantida, Pakakasama, Samart, Chuansumrit, Ampaiwan, Putawornsub, Nattaphat, Sirasittikarn, Sawitt, Wantanawijarn, Sataporn, Kadegasem, Praguywan, Hongeng, Suradej, Sirachainan, Nongnuch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739460/
https://www.ncbi.nlm.nih.gov/pubmed/33327955
http://dx.doi.org/10.1186/s12959-020-00232-z
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author Lertthammakiat, Surapong
Sitthirat, Peerasit
Anurathapan, Usanarat
Songdej, Duantida
Pakakasama, Samart
Chuansumrit, Ampaiwan
Putawornsub, Nattaphat
Sirasittikarn, Sawitt
Wantanawijarn, Sataporn
Kadegasem, Praguywan
Hongeng, Suradej
Sirachainan, Nongnuch
author_facet Lertthammakiat, Surapong
Sitthirat, Peerasit
Anurathapan, Usanarat
Songdej, Duantida
Pakakasama, Samart
Chuansumrit, Ampaiwan
Putawornsub, Nattaphat
Sirasittikarn, Sawitt
Wantanawijarn, Sataporn
Kadegasem, Praguywan
Hongeng, Suradej
Sirachainan, Nongnuch
author_sort Lertthammakiat, Surapong
collection PubMed
description Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, including thrombin antithrombin complex, prothrombin fragment, D-dimer, von Willebrand factor antigen and thrombomodulin levels, were not significantly different between haploidentical and matched-donor HSCT patients.
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spelling pubmed-77394602020-12-17 No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease Lertthammakiat, Surapong Sitthirat, Peerasit Anurathapan, Usanarat Songdej, Duantida Pakakasama, Samart Chuansumrit, Ampaiwan Putawornsub, Nattaphat Sirasittikarn, Sawitt Wantanawijarn, Sataporn Kadegasem, Praguywan Hongeng, Suradej Sirachainan, Nongnuch Thromb J Letter to the Editor Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, including thrombin antithrombin complex, prothrombin fragment, D-dimer, von Willebrand factor antigen and thrombomodulin levels, were not significantly different between haploidentical and matched-donor HSCT patients. BioMed Central 2020-09-04 /pmc/articles/PMC7739460/ /pubmed/33327955 http://dx.doi.org/10.1186/s12959-020-00232-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Lertthammakiat, Surapong
Sitthirat, Peerasit
Anurathapan, Usanarat
Songdej, Duantida
Pakakasama, Samart
Chuansumrit, Ampaiwan
Putawornsub, Nattaphat
Sirasittikarn, Sawitt
Wantanawijarn, Sataporn
Kadegasem, Praguywan
Hongeng, Suradej
Sirachainan, Nongnuch
No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title_full No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title_fullStr No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title_full_unstemmed No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title_short No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
title_sort no differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739460/
https://www.ncbi.nlm.nih.gov/pubmed/33327955
http://dx.doi.org/10.1186/s12959-020-00232-z
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