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Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis

BACKGROUND: The breathing disorder obstructive sleep apnea syndrome (OSAS) only occurs while asleep. While polysomnography (PSG) represents the premiere standard for diagnosing OSAS, it is quite costly, complicated to use, and carries a significant delay between testing and diagnosis. METHODS: This...

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Autores principales: Ma, Bin, Wu, Zhaolong, Li, Shengyu, Benton, Ryan, Li, Dongqi, Huang, Yulong, Kasukurthi, Mohan Vamsi, Lin, Jingwei, Borchert, Glen M., Tan, Shaobo, Li, Gang, Yang, Meihong, Huang, Jingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739462/
https://www.ncbi.nlm.nih.gov/pubmed/33323112
http://dx.doi.org/10.1186/s12911-020-01329-1
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author Ma, Bin
Wu, Zhaolong
Li, Shengyu
Benton, Ryan
Li, Dongqi
Huang, Yulong
Kasukurthi, Mohan Vamsi
Lin, Jingwei
Borchert, Glen M.
Tan, Shaobo
Li, Gang
Yang, Meihong
Huang, Jingshan
author_facet Ma, Bin
Wu, Zhaolong
Li, Shengyu
Benton, Ryan
Li, Dongqi
Huang, Yulong
Kasukurthi, Mohan Vamsi
Lin, Jingwei
Borchert, Glen M.
Tan, Shaobo
Li, Gang
Yang, Meihong
Huang, Jingshan
author_sort Ma, Bin
collection PubMed
description BACKGROUND: The breathing disorder obstructive sleep apnea syndrome (OSAS) only occurs while asleep. While polysomnography (PSG) represents the premiere standard for diagnosing OSAS, it is quite costly, complicated to use, and carries a significant delay between testing and diagnosis. METHODS: This work describes a novel architecture and algorithm designed to efficiently diagnose OSAS via the use of smart phones. In our algorithm, features are extracted from the data, specifically blood oxygen saturation as represented by SpO2. These features are used by a support vector machine (SVM) based strategy to create a classification model. The resultant SVM classification model can then be employed to diagnose OSAS. To allow remote diagnosis, we have combined a simple monitoring system with our algorithm. The system allows physiological data to be obtained from a smart phone, the data to be uploaded to the cloud for processing, and finally population of a diagnostic report sent back to the smart phone in real-time. RESULTS: Our initial evaluation of this algorithm utilizing actual patient data finds its sensitivity, accuracy, and specificity to be 87.6%, 90.2%, and 94.1%, respectively. DISCUSSION: Our architecture can monitor human physiological readings in real time and give early warning of abnormal physiological parameters. Moreover, after our evaluation, we find 5G technology offers higher bandwidth with lower delays ensuring more effective monitoring. In addition, we evaluate our algorithm utilizing real-world data; the proposed approach has high accuracy, sensitivity, and specific, demonstrating that our approach is very promising. CONCLUSIONS: Experimental results on the apnea data in University College Dublin (UCD) Database have proven the efficiency and effectiveness of our methodology. This work is a pilot project and still under development. There is no clinical validation and no support. In addition, the Internet of Things (IoT) architecture enables real-time monitoring of human physiological parameters, combined with diagnostic algorithms to provide early warning of abnormal data.
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spelling pubmed-77394622020-12-17 Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis Ma, Bin Wu, Zhaolong Li, Shengyu Benton, Ryan Li, Dongqi Huang, Yulong Kasukurthi, Mohan Vamsi Lin, Jingwei Borchert, Glen M. Tan, Shaobo Li, Gang Yang, Meihong Huang, Jingshan BMC Med Inform Decis Mak Research BACKGROUND: The breathing disorder obstructive sleep apnea syndrome (OSAS) only occurs while asleep. While polysomnography (PSG) represents the premiere standard for diagnosing OSAS, it is quite costly, complicated to use, and carries a significant delay between testing and diagnosis. METHODS: This work describes a novel architecture and algorithm designed to efficiently diagnose OSAS via the use of smart phones. In our algorithm, features are extracted from the data, specifically blood oxygen saturation as represented by SpO2. These features are used by a support vector machine (SVM) based strategy to create a classification model. The resultant SVM classification model can then be employed to diagnose OSAS. To allow remote diagnosis, we have combined a simple monitoring system with our algorithm. The system allows physiological data to be obtained from a smart phone, the data to be uploaded to the cloud for processing, and finally population of a diagnostic report sent back to the smart phone in real-time. RESULTS: Our initial evaluation of this algorithm utilizing actual patient data finds its sensitivity, accuracy, and specificity to be 87.6%, 90.2%, and 94.1%, respectively. DISCUSSION: Our architecture can monitor human physiological readings in real time and give early warning of abnormal physiological parameters. Moreover, after our evaluation, we find 5G technology offers higher bandwidth with lower delays ensuring more effective monitoring. In addition, we evaluate our algorithm utilizing real-world data; the proposed approach has high accuracy, sensitivity, and specific, demonstrating that our approach is very promising. CONCLUSIONS: Experimental results on the apnea data in University College Dublin (UCD) Database have proven the efficiency and effectiveness of our methodology. This work is a pilot project and still under development. There is no clinical validation and no support. In addition, the Internet of Things (IoT) architecture enables real-time monitoring of human physiological parameters, combined with diagnostic algorithms to provide early warning of abnormal data. BioMed Central 2020-12-15 /pmc/articles/PMC7739462/ /pubmed/33323112 http://dx.doi.org/10.1186/s12911-020-01329-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Ma, Bin
Wu, Zhaolong
Li, Shengyu
Benton, Ryan
Li, Dongqi
Huang, Yulong
Kasukurthi, Mohan Vamsi
Lin, Jingwei
Borchert, Glen M.
Tan, Shaobo
Li, Gang
Yang, Meihong
Huang, Jingshan
Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title_full Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title_fullStr Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title_full_unstemmed Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title_short Development of a support vector machine learning and smart phone Internet of Things-based architecture for real-time sleep apnea diagnosis
title_sort development of a support vector machine learning and smart phone internet of things-based architecture for real-time sleep apnea diagnosis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739462/
https://www.ncbi.nlm.nih.gov/pubmed/33323112
http://dx.doi.org/10.1186/s12911-020-01329-1
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