Cargando…

Notch3 and its CADASIL mutants differentially regulate cellular phenotypes

Notch3 is a member of the Notch family and its mutations are known to cause a hereditary human disorder called cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). However, the specific function and signaling cascade initiated by CADASIL mutants remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chunjing, Huang, Ziyang, Zhou, Riyong, Zhou, Ying, Shentu, Yangping, Yu, Kang, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739825/
https://www.ncbi.nlm.nih.gov/pubmed/33335580
http://dx.doi.org/10.3892/etm.2020.9549