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Minimally Invasive Esophagectomy for Achieving R0
BACKGROUND: Minimally invasive esophagectomy (MIE) is becoming increasing popular. Since it was introduced, there has been debate about its safety and efficacy when compared with open esophagectomies (OE). We sought to compare the oncologic outcomes of MIE and OE in this study specifically with rega...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Laparoendoscopic Surgeons
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739842/ https://www.ncbi.nlm.nih.gov/pubmed/33414613 http://dx.doi.org/10.4293/JSLS.2020.00060 |
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author | Darwish, Muhammad B. Nagatomo, Kei Jackson, Terence Cho, Edward Osman, Houssam Jeyarajah, D. Rohan |
author_facet | Darwish, Muhammad B. Nagatomo, Kei Jackson, Terence Cho, Edward Osman, Houssam Jeyarajah, D. Rohan |
author_sort | Darwish, Muhammad B. |
collection | PubMed |
description | BACKGROUND: Minimally invasive esophagectomy (MIE) is becoming increasing popular. Since it was introduced, there has been debate about its safety and efficacy when compared with open esophagectomies (OE). We sought to compare the oncologic outcomes of MIE and OE in this study specifically with regards to margin status and nodal retrieval. METHODS: Ninety-three patients that underwent MIE (76/93) or OE (17/93) for esophageal cancer at out institution between January 2013 and September 2018 were retrospectively reviewed. Histological type, pathological tumor grading, clinical tumor staging (cTNM), pathological tumor staging (pTNM), post-neoadjuvant tumor staging (ypTNM), and lymph node retrieval were obtained and compared. RESULTS: The results show a statistically significant improvement in resection margins (R0) in the MIE group when compared with the OE group. Other oncologic parameters including clinical staging, pathologic staging, tumor grade, neoadjuvant therapy (NAT), and nodal retrieval were not statistically significantly different between the open and MIE groups. CONCLUSION: The improvement in short-term surgical outcomes in MIE is well established. This study demonstrates that MIE can have superior surgical oncologic outcomes compared to OE, this was specifically an improved R0 margin rate with MIE compared to OE. These results further support the use of MIE in the treatment of esophageal cancer. |
format | Online Article Text |
id | pubmed-7739842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Society of Laparoendoscopic Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-77398422021-01-06 Minimally Invasive Esophagectomy for Achieving R0 Darwish, Muhammad B. Nagatomo, Kei Jackson, Terence Cho, Edward Osman, Houssam Jeyarajah, D. Rohan JSLS Research Article BACKGROUND: Minimally invasive esophagectomy (MIE) is becoming increasing popular. Since it was introduced, there has been debate about its safety and efficacy when compared with open esophagectomies (OE). We sought to compare the oncologic outcomes of MIE and OE in this study specifically with regards to margin status and nodal retrieval. METHODS: Ninety-three patients that underwent MIE (76/93) or OE (17/93) for esophageal cancer at out institution between January 2013 and September 2018 were retrospectively reviewed. Histological type, pathological tumor grading, clinical tumor staging (cTNM), pathological tumor staging (pTNM), post-neoadjuvant tumor staging (ypTNM), and lymph node retrieval were obtained and compared. RESULTS: The results show a statistically significant improvement in resection margins (R0) in the MIE group when compared with the OE group. Other oncologic parameters including clinical staging, pathologic staging, tumor grade, neoadjuvant therapy (NAT), and nodal retrieval were not statistically significantly different between the open and MIE groups. CONCLUSION: The improvement in short-term surgical outcomes in MIE is well established. This study demonstrates that MIE can have superior surgical oncologic outcomes compared to OE, this was specifically an improved R0 margin rate with MIE compared to OE. These results further support the use of MIE in the treatment of esophageal cancer. Society of Laparoendoscopic Surgeons 2020 /pmc/articles/PMC7739842/ /pubmed/33414613 http://dx.doi.org/10.4293/JSLS.2020.00060 Text en © 2020 by JSLS, Journal of the Society of Laparoscopic & Robotic Surgeons. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/us/), which permits for noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not altered in any way. |
spellingShingle | Research Article Darwish, Muhammad B. Nagatomo, Kei Jackson, Terence Cho, Edward Osman, Houssam Jeyarajah, D. Rohan Minimally Invasive Esophagectomy for Achieving R0 |
title | Minimally Invasive Esophagectomy for Achieving R0 |
title_full | Minimally Invasive Esophagectomy for Achieving R0 |
title_fullStr | Minimally Invasive Esophagectomy for Achieving R0 |
title_full_unstemmed | Minimally Invasive Esophagectomy for Achieving R0 |
title_short | Minimally Invasive Esophagectomy for Achieving R0 |
title_sort | minimally invasive esophagectomy for achieving r0 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739842/ https://www.ncbi.nlm.nih.gov/pubmed/33414613 http://dx.doi.org/10.4293/JSLS.2020.00060 |
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