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Dexmedetomidine protects against endothelial injury in septic rats induced by cecal ligation and puncture by decreasing angiopoietin 2 and increasing vascular endothelial cadherin levels

The aim of the present study was to investigate the protective effect of dexmedetomidine (Dex) on endothelial injury in a cecal ligation and puncture (CLP)-induced rat model of sepsis. A total of 36 male Sprague-Dawley rats were divided into three groups: Sham, CLP and CLP + Dex. The wet/dry (W/D) r...

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Detalles Bibliográficos
Autores principales:	Zhang, Peng, Peng, Ji, Ren, Yun-Qin, Zheng, Han, Yan, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739856/ https://www.ncbi.nlm.nih.gov/pubmed/33335574 http://dx.doi.org/10.3892/etm.2020.9543

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