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A novel danshensu/tetramethypyrazine derivative attenuates oxidative stress-induced autophagy injury via the AMPK-mTOR-Ulk1 signaling pathway in cardiomyocytes

Myocardial ischemia/reperfusion injury (MIRI) is an inevitable and unsolved clinical problem in the treatment of ischemic heart diseases. Compound DT-010 is a novel danshensu/tetramethylpyrazine derivative and was examined as a candidate for treating MIRI. In the present study, MTT, lactate dehydrog...

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Detalles Bibliográficos
Autores principales:	Xie, Caipeng, Luo, Jingxiong, Hu, Huihui, Wang, Liang, Yu, Pei, Xu, Lipeng, Sun, Yewei, Wang, Yuqiang, Shan, Luchen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739857/ https://www.ncbi.nlm.nih.gov/pubmed/33335581 http://dx.doi.org/10.3892/etm.2020.9550

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