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TLR4/MD-2 is a receptor for extracellular nucleophosmin 1

Nucleophosmin 1 (NPM1) primarily localizes to the nucleus and is passively released into the extracellular milieu by necrotic or damaged cells, or is secreted by monocytes and macrophages. Extracellular NPM1 acts as a potent inflammatory stimulator by promoting cytokine production [e.g., tumor necro...

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Detalles Bibliográficos
Autores principales:	Nakatomi, Kota, Ueno, Hikari, Ishikawa, Yuto, Salim, Ronny Christiadi, Mori, Yuki, Kanemoto, Issey, Tancharoen, Salunya, Kikuchi, Kiyoshi, Miura, Naoki, Omori, Taketo, Okuda-Ashitaka, Emiko, Matsumura, Kiyoshi, Imaizumi, Hitoshi, Motomiya, Yoshihiro, Maruyama, Ikuro, Kawahara, Ko-Ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739869/ https://www.ncbi.nlm.nih.gov/pubmed/33335727 http://dx.doi.org/10.3892/br.2020.1397

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