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The CAR T‐Cell Mechanoimmunology at a Glance

Chimeric antigen receptor (CAR) T‐cell transfer is a novel paradigm of adoptive T‐cell immunotherapy. When coming into contact with a target cancer cell, CAR T‐cell forms a nonclassical immunological synapse with the cancer cell and dynamically orchestrates multiple critical forces to commit cytotox...

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Detalles Bibliográficos
Autores principales: Li, Rui, Ma, Chao, Cai, Haogang, Chen, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740088/
https://www.ncbi.nlm.nih.gov/pubmed/33344135
http://dx.doi.org/10.1002/advs.202002628