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An Approach to Identify New Pleiotropic Genetic Loci From Publicly Available Univariate GWAS Results
The connections between genes and multifactorial polygenic age-related traits are not trivial due to complexity of metabolic networks in an organism, which were primarily adapted to maximize fitness at reproductive age in ancient environments. Given this complexity, pleiotropy in predisposition to c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740484/ http://dx.doi.org/10.1093/geroni/igaa057.426 |