Cargando…

Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long-Term Survival

As in-hospital sepsis mortality has decreased, more “sepsis survivors” are progressing into poorly characterized long-term outcomes. The purpose of this study was to describe the current epidemiology of sepsis in older adults compared to middle-aged and young adults. Design: Prospective longitudinal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mankowski, Robert, Anton, Stephen, Ghita, Gabriela, Leeuwenburgh, Christiaan, Moldawer, Lyle, Efron, Philip, Brakenridge, Scott, Moore, Frederick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740927/ http://dx.doi.org/10.1093/geroni/igaa057.454

Ejemplares similares

Older adults show biomarker evidence of PICS after sepsis
por: Mankowski, Robert, et al.
Publicado: (2021)

195 Older adults show biomarker evidence of PICS after sepsis
por: Mankowski, Robert, et al.
Publicado: (2022)

Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors
por: Custodero, Carlo, et al.
Publicado: (2019)

The impact of sarcopenia and acute muscle mass loss on long‐term outcomes in critically ill patients with intra‐abdominal sepsis
por: Cox, Michael C., et al.
Publicado: (2021)

Lipid and lipoprotein predictors of functional outcomes and long-term mortality after surgical sepsis
por: Guirgis, Faheem W., et al.
Publicado: (2021)

Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors
por: Darden, Dijoia B., et al.
Publicado: (2021)

Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients
por: Loftus, Tyler J, et al.
Publicado: (2017)

Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study
por: Stortz, Julie A., et al.
Publicado: (2020)

Immunological Endotyping of Chronic Critical Illness After Severe Sepsis
por: Fenner, Brittany P., et al.
Publicado: (2021)

Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness
por: Barker, Grant, et al.
Publicado: (2021)

A Review of GM-CSF Therapy in Sepsis
por: Mathias, Brittany, et al.
Publicado: (2015)

Sex differences associate with late microbiome alterations after murine surgical sepsis
por: Efron, Philip Alexander, et al.
Publicado: (2022)

HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock
por: Guirgis, Faheem W., et al.
Publicado: (2018)

A Transcriptomic Severity Metric That Predicts Clinical Outcomes in Critically Ill Surgical Sepsis Patients
por: Brakenridge, Scott C., et al.
Publicado: (2021)

Host Responses to Sepsis Vary in Different Low-Lethality Murine Models
por: Gentile, Lori F., et al.
Publicado: (2014)

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome
por: Hawkins, Russell B., et al.
Publicado: (2018)

Defining critical illness using immunological endotypes in patients with and without of sepsis: A cohort study
por: Balch, Jeremy A., et al.
Publicado: (2023)

Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study
por: Balch, Jeremy A., et al.
Publicado: (2023)

LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock
por: Guirgis, Faheem W, et al.
Publicado: (2019)

Discovery and Validation of Urinary Molecular Signature of Early Sepsis
por: Bandyopadhyay, Sabyasachi, et al.
Publicado: (2020)

Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock
por: Vanzant, Erin L, et al.
Publicado: (2015)

Lipid intensive drug therapy for sepsis pilot: A Bayesian phase I clinical trial
por: Guirgis, Faheem W., et al.
Publicado: (2020)

Dysregulated Immunity and Immunotherapy after Sepsis
por: Darden, Dijoia B., et al.
Publicado: (2021)

Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis
por: Hollen, McKenzie K., et al.
Publicado: (2019)

Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults
por: Raymond, Steven L., et al.
Publicado: (2018)

Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis
por: Loftus, Tyler J., et al.
Publicado: (2021)

Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients
por: Brakenridge, Scott C., et al.
Publicado: (2022)

Pathophysiology and Treatment Strategies of Acute Myopathy and Muscle Wasting after Sepsis
por: Mankowski, Robert T., et al.
Publicado: (2021)

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy
por: Horiguchi, Hiroyuki, et al.
Publicado: (2018)

Immunotherapies for COVID-19: lessons learned from sepsis
por: Remy, Kenneth E, et al.
Publicado: (2020)

Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma
por: Stortz, Julie A., et al.
Publicado: (2019)

Age and Sex Influence the Hippocampal Response and Recovery Following Sepsis
por: Barter, Jolie, et al.
Publicado: (2019)

CXCR3 blockade: a novel anti-sepsis approach?
por: Delano, Matthew J, et al.
Publicado: (2012)

A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes
por: Guirgis, Faheem W., et al.
Publicado: (2021)

Influence of age and sex on microRNA response and recovery in the hippocampus following sepsis
por: Rani, Asha, et al.
Publicado: (2022)

Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection
por: Polcz, Valerie E., et al.
Publicado: (2023)

Unique transcriptomic response to sepsis is observed among patients of different age groups
por: Raymond, Steven L., et al.
Publicado: (2017)

Disability and Symptom Burden Among the Very Old: Comparison of Survivors and Decedents
por: Liu, Xinran, et al.
Publicado: (2020)

Resveratrol and exercise to treat functional limitations in late life: Design of a randomized controlled trial
por: Layne, Andrew S., et al.
Publicado: (2017)

Relationship between Mitochondrial Quality Control Markers, Lower Extremity Tissue Composition, and Physical Performance in Physically Inactive Older Adults
por: Picca, Anna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4o36bu1e9gio7dfa25gd4lvvr0