Cargando…
Aging Related Transcriptomic Changes in the Mouse Models of Alzheimer’s Disease
Alzheimer’s Disease (AD) is characterized by multiple clinical phenotypes and molecular signatures at different stages of the disease and aging is the major risk factor for sporadic AD. Aging and AD are linked at molecular, cellular and systems level with commonalities in inflammation and associated...
Autores principales: | Uyar, Asli, Pandey, Ravi, Preuss, Christoph, Kotredes, Kevin, Howell, Gareth, Sasner, Michael, Carter, Gregory |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741058/ http://dx.doi.org/10.1093/geroni/igaa057.385 |
Ejemplares similares
-
Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer’s disease
por: Pandey, Ravi S., et al.
Publicado: (2023) -
Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease
por: Pandey, Ravi S., et al.
Publicado: (2019) -
A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
por: Preuss, Christoph, et al.
Publicado: (2020) -
Determining the Role of ApoE4 in Age-Related Cerebrovascular Decline
por: Foley, Kate, et al.
Publicado: (2020) -
The APOE(ε3/ε4) Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
por: Foley, Kate E., et al.
Publicado: (2022)